Multiscale modeling for biologists

Multiscale modeling for epitaxial growth

Epitaxy is the growth of a thin film on a substrate in which the crystal properties of the film are inherited from those of the substrate. Because of the wide range of relevant length and time scales, multiscale mathematical models have been developed to describe epitaxial growth. This presentation describes atomistic, island dynamics and continuum models. Island dynamics models are multiscale ...

Genetic Programming for Multiscale Modeling

We propose the use of genetic programming (GP)—a genetic algorithm that evolves computer programs—for bridging simulation methods across multiple scales of time and/or length. The effectiveness of genetic programming in multiscale simulation is demonstrated using two illustrative, non-trivial case studies in science and engineering. The first case is multi-timescale materials kinetics modeling,...

Multiscale modeling

Principles of Multiscale Modeling

Multiscale Modeling of Malaria

Parasitic infectious diseases like malaria and certain hereditary hematologic disorders are often associated with major changes in the shape and viscoelastic properties of red blood cells. Such changes can disrupt blood flow and, possibly, brain perfusion, as in the case of cerebral malaria. In recent work on stochastic multiscale models—in conjunction with large-scale parallel computing—we wer...